Non-cirrhotic portal fibrosis

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Non-cirrhotic portal fibrosis
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Non-cirrhotic portal fibrosis (NCPF) is a chronic liver disease<ref>, 

 Non-cirrhotic portal fibrosis: one disease with many names? An analysis from morphological study of native explant livers with end stage chronic liver disease., 
 Journal of Clinical Pathology, 
 
 Vol. 64(Issue: 7),
 pp. 592–8,
 DOI: 10.1136/jcp.2010.087395,
 PMID: 21685145,</ref> and type of non-cirrhotic portal hypertension (NCPH).

Presentation[edit]

It is characterized by 'obliterative portovenopathy', which leads to various problems such as portal hypertension, massive splenomegaly, and variceal bleeding. It is estimated that about 85% of people with NCPF have repeated episodes of variceal bleeding.<ref>, 

 Non-cirrhotic portal fibrosis., 
 Journal of Gastroenterology and Hepatology, 
 
 Vol. 17 Suppl 3,
 pp. S214-23,
 
 PMID: 12472939,</ref>

Diagnosis[edit]

Hallmark of the disease is thrombosis/sclerosis of branches of portal vein. Vessels formed are often termed as mesangiosinusoids or periportal cavernoma.

Treatment[edit]


References[edit]

External links[edit]


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