Nissl bodies
Nissl Bodies
Nissl bodies (pronounced: Niss-ul bodies) are large granular bodies found in neurons. They are named after the German psychiatrist and neuropathologist Franz Nissl, who first described them at the end of the 19th century.
Etymology
The term "Nissl bodies" is derived from the name of Franz Nissl, who extensively studied the pathology of the nervous system and contributed significantly to the field of Neuropathology.
Definition
Nissl bodies are essentially rough Endoplasmic reticulum with rosettes of free ribosomes, and are the site of protein synthesis. They are found in the cell body and dendrites of neurons, but not in the axon, and are most prominent in motor neurons.
Function
The primary function of Nissl bodies is to produce proteins for the nerve cell. They are responsible for the synthesis of protein molecules which are used in the repair of damaged neurons, and also play a role in the production of neurotransmitters.
Related Terms
- Neuron: The basic working unit of the brain, a specialized cell designed to transmit information to other nerve cells, muscle, or gland cells.
- Endoplasmic reticulum: A type of organelle in the cells of eukaryotic organisms that forms an interconnected network of flattened, membrane-enclosed sacs or tubes known as cisternae.
- Neurotransmitter: Chemicals that transmit signals across a synapse from one neuron (nerve cell) to another 'target' neuron, muscle cell, or gland cell.
See Also
External links
- Medical encyclopedia article on Nissl bodies
- Wikipedia's article - Nissl bodies
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