Nisin

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Nisin

Nisin (pronounced /ˈnaɪsɪn/) is a polycyclic antibacterial peptide produced by the bacterium Lactococcus lactis that is used as a food preservative. It has 34 amino acid residues, including the uncommon amino acids lanthionine (Lan), methyllanthionine (MeLan), didehydroalanine (Dha) and didehydroaminobutyric acid (Dhb).

Etymology

The term "Nisin" is derived from Nisus, the genus name of the bacteria that produces it, and '-in', a common suffix used in biochemistry to denote proteins or peptides.

Production

Lactococcus lactis, the bacterium that produces nisin, is typically grown in a nutrient broth, an environment that promotes the production of the peptide. The peptide is then extracted and purified for use as a food preservative.

Uses

Nisin is used as a preservative in various foods, including dairy products, meats, and beverages. It is effective against a wide range of harmful bacteria, including Listeria monocytogenes, Staphylococcus aureus, and Clostridium botulinum, among others.

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