Nialamide
Nialamide
Nialamide (pronounced: ny-AL-uh-mide) is a non-selective, irreversible Monoamine oxidase inhibitor (MAOI) that was used as an antidepressant in the 1950s and 1960s, but has since been discontinued.
Etymology
The term "Nialamide" is derived from the chemical name N-benzyl-isoamyl-amide. The prefix "Nia-" comes from the N-benzyl part of the chemical name, "-lam-" comes from the isoamyl part, and "-ide" is a common suffix used in chemistry to denote a specific type of compound.
Usage
Nialamide was primarily used as an antidepressant. It works by inhibiting the action of a group of enzymes known as monoamine oxidases, which are involved in the breakdown of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. By inhibiting these enzymes, Nialamide increases the levels of these neurotransmitters in the brain, which can help to alleviate the symptoms of depression.
Related Terms
- Monoamine oxidase inhibitor (MAOI): A type of drug that inhibits the action of monoamine oxidase enzymes, thereby increasing the levels of certain neurotransmitters in the brain.
- Antidepressant: A type of medication used to treat depression and other mood disorders.
- Neurotransmitter: A chemical substance that transmits nerve impulses across a synapse.
- Serotonin: A neurotransmitter that is involved in the regulation of mood, appetite, and sleep.
- Norepinephrine: A neurotransmitter that is involved in the regulation of attention and responding actions.
- Dopamine: A neurotransmitter that is involved in the regulation of movement, mood, and reward.
External links
- Medical encyclopedia article on Nialamide
- Wikipedia's article - Nialamide
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