Neutropenic enterocolitis

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Neutropenic enterocolitis (pronunciation: noo-troh-PEE-nik en-ter-oh-co-LIE-tis), also known as typhlitis, is a medical condition that affects the intestines. It is characterized by inflammation and necrosis of the cecum, although it can extend to other parts of the colon.

Etymology

The term "neutropenic enterocolitis" is derived from the words "neutropenia", which refers to a decrease in the number of neutrophils (a type of white blood cell), and "enterocolitis", which means inflammation of the intestine. The term "typhlitis" comes from the Greek word "typhlon", meaning "blind", referring to the cecum's blind-ended nature.

Symptoms

Patients with neutropenic enterocolitis may experience a range of symptoms, including abdominal pain, diarrhea, fever, and nausea. In severe cases, the condition can lead to sepsis and shock.

Causes

Neutropenic enterocolitis is most commonly seen in patients with neutropenia, particularly those undergoing chemotherapy for cancer. The condition is thought to occur due to a combination of mucosal injury from chemotherapy and decreased immune response due to neutropenia.

Diagnosis

Diagnosis of neutropenic enterocolitis is typically based on clinical symptoms and imaging studies, such as computed tomography (CT) scans.

Treatment

Treatment for neutropenic enterocolitis typically involves antibiotics, intravenous fluids, and pain management. In severe cases, surgery may be required.

See also

External links

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