Neurosyphilis

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Neurosyphilis

Neurosyphilis (/ˌnʊəroʊˈsɪfɪlɪs/) is a specific form of syphilis, a sexually transmitted infection, that involves infection of the brain and spinal cord.

Etymology

The term "neurosyphilis" is derived from the Greek words "neuron" meaning nerve and "syphilis" named after the character Syphilus in a poem by the Italian physician and poet Girolamo Fracastoro.

Symptoms

Neurosyphilis usually occurs about 10 to 20 years after the initial syphilis infection. There are four different forms of neurosyphilis: asymptomatic, meningovascular, tabes dorsalis, and general paresis. Symptoms can vary widely, depending on the form of neurosyphilis. Common symptoms include headache, vertigo, poor concentration, irritability, loss of memory, stroke, sensory deficits, and mental disturbances.

Diagnosis

Diagnosis of neurosyphilis involves a physical examination, a neurological examination, blood tests, and a spinal tap to examine the cerebrospinal fluid.

Treatment

Treatment for neurosyphilis typically involves intravenous penicillin for a period of 10 to 14 days. Follow-up blood tests are usually performed at 3, 6, 12, 24, and 36 months to ensure the infection has been fully treated.

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