Neuroblast

Neuroblast is a type of cell that is involved in the development of the nervous system. It is a precursor cell, meaning that it has the potential to develop into several different types of cells within the nervous system. Neuroblasts are found in the developing nervous system of embryos and in the bone marrow of adults.

Development

Neuroblasts originate from neural stem cells, which are multipotent stem cells that can give rise to both neurons and glial cells. The process of neuroblast development is regulated by a complex network of genes and signaling pathways. This process is crucial for the formation of the nervous system during embryonic development.

Function

Neuroblasts have the ability to divide and differentiate into neurons, the primary cells of the nervous system. They also have the ability to migrate to different parts of the nervous system where they are needed. This ability is crucial for the proper formation and function of the nervous system.

Clinical significance

Abnormalities in neuroblast development can lead to a variety of neurological disorders. For example, neuroblastoma is a type of cancer that arises from neuroblasts and primarily affects children. Other disorders, such as certain types of neurodegenerative diseases, may also be linked to abnormalities in neuroblast function.

See also

• Neuron
• Neural stem cell
• Neuroblastoma
• Neurodegenerative disease

References

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