Naphthylmetrazine

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Overview of the chemical compound Naphthylmetrazine


Structure of Naphthylmetrazine

Naphthylmetrazine is a chemical compound that belongs to the class of stimulants. It is structurally related to phenylmorpholines and is known for its psychoactive properties. This compound has been studied for its potential effects on the central nervous system, although it is not widely used in clinical practice.

Chemical Structure and Properties

Naphthylmetrazine is characterized by its unique chemical structure, which includes a naphthyl group attached to a morpholine ring. The presence of the naphthyl group distinguishes it from other phenylmorpholine derivatives. The molecular formula of Naphthylmetrazine is C14H17NO, and it has a molar mass of 215.29 g/mol.

Pharmacology

Naphthylmetrazine acts primarily as a central nervous system stimulant. It is believed to exert its effects by increasing the levels of certain neurotransmitters, such as dopamine and norepinephrine, in the brain. This action is similar to that of other stimulants, which can lead to increased alertness, energy, and euphoria.

Mechanism of Action

The exact mechanism of action of Naphthylmetrazine is not fully understood. However, it is thought to inhibit the reuptake of dopamine and norepinephrine, leading to increased concentrations of these neurotransmitters in the synaptic cleft. This results in enhanced neurotransmission and stimulation of the central nervous system.

Potential Uses

While Naphthylmetrazine has been studied for its stimulant properties, it has not been widely adopted for medical use. Research into its potential applications is limited, and it is not approved for therapeutic use in most countries. However, its structural similarity to other stimulants suggests potential uses in conditions such as attention deficit hyperactivity disorder (ADHD) and narcolepsy, although further research is needed.

Safety and Side Effects

The safety profile of Naphthylmetrazine is not well-documented, as it is not commonly used in clinical settings. Potential side effects may include those typical of stimulant drugs, such as increased heart rate, elevated blood pressure, insomnia, and anxiety. Long-term use could potentially lead to dependence and other adverse effects.

Legal Status

Naphthylmetrazine is not a controlled substance in many jurisdictions, but its legal status can vary. It is important to consult local regulations regarding its use and distribution.

Related Compounds

Naphthylmetrazine is related to other phenylmorpholine derivatives, such as phenmetrazine and methylphenidate. These compounds share similar stimulant effects and mechanisms of action.

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Contributors: Prab R. Tumpati, MD