NDV-HXP-S

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NDV-HXP-S

NDV-HXP-S (pronounced as N-D-V-H-X-P-S) is a novel vaccine candidate for the prevention of COVID-19. It is developed by the Program for Appropriate Technology in Health (PATH) and the Government Pharmaceutical Organization (GPO) of Thailand.

Etymology

The term NDV-HXP-S is an acronym derived from the components used in the vaccine's development. NDV stands for Newcastle Disease Virus, a type of virus used as a vector in the vaccine. HXP refers to the HexaPro, a version of the SARS-CoV-2 spike protein. S stands for Spike, the protein on the surface of the SARS-CoV-2 virus that the vaccine targets.

Development and Mechanism

The NDV-HXP-S vaccine uses a modified version of the Newcastle Disease Virus to carry the HexaPro version of the SARS-CoV-2 spike protein into the body. This stimulates an immune response, producing antibodies that can recognize and neutralize the SARS-CoV-2 virus if the person is exposed in the future.

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