N-Terminal domain antiandrogen

N-Terminal Domain Antiandrogen

The N-Terminal Domain Antiandrogen (pronunciation: N-Terminal: /ɛnˈtɜːrmɪnəl/, Domain: /dəˈmeɪn/, Antiandrogen: /ˌæntiˈændrədʒən/) is a type of Antiandrogen that specifically targets the N-terminal domain of the Androgen Receptor.

Etymology

The term "N-Terminal Domain Antiandrogen" is derived from the three components it targets. "N-Terminal" refers to the start of a protein or polypeptide terminated by an amino acid with a free amine group (-NH2). "Domain" in this context refers to a specific region of a protein that can exist and function independently of the rest of the protein chain. "Antiandrogen" refers to any compound that inhibits the biological effects of androgens, male sex hormones, by blocking the appropriate receptors.

Function

N-Terminal Domain Antiandrogens function by binding to the N-terminal domain of the androgen receptor, thereby inhibiting the receptor's ability to bind with androgens. This prevents the androgens from exerting their biological effects, which can be beneficial in conditions where androgen activity is undesirable, such as Prostate Cancer.

Related Terms

• Androgen Receptor: A type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone.
• Antiandrogen: Any compound that inhibits the biological effects of androgens, male sex hormones, by blocking the appropriate receptors.
• Prostate Cancer: A form of cancer that develops in the prostate, a gland in the male reproductive system. It is often treated with antiandrogens.

See Also

• C-Terminal Domain Antiandrogen
• Selective Androgen Receptor Modulator
• Androgen Deprivation Therapy

External links

• Medical encyclopedia article on N-Terminal domain antiandrogen
• Wikipedia's article - N-Terminal domain antiandrogen

This WikiMD article is a stub. You can help make it a full article.

---

Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski