Multifactorial

From WikiMD's medical encyclopedia

Multifactorial refers to a trait or disorder determined by multiple genes on different chromosomes, combined with environmental factors. Multifactorial disorders include heart disease, high blood pressure, Alzheimer's disease, arthritis, diabetes, cancer, and obesity.

Genetics

Multifactorial inheritance, also known as polygenic inheritance, is a type of non-Mendelian inheritance. Unlike Mendelian inheritance, where traits are controlled by a single gene, multifactorial traits are controlled by multiple genes and environmental factors.

Environmental Factors

Environmental factors play a significant role in the expression of multifactorial traits. These factors can include diet, exercise, exposure to toxins, and stress. The interaction between genetic factors and environmental factors can lead to a wide range of phenotypic outcomes.

Disorders

Multifactorial disorders are common and include a wide range of conditions. These disorders often have a significant impact on an individual's health and quality of life. Some examples of multifactorial disorders include:

Prevention and Treatment

Prevention and treatment of multifactorial disorders often involve lifestyle changes and medication. Genetic counseling may also be beneficial for individuals with a family history of a multifactorial disorder.

See Also

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