Mpox in the Democratic Republic of the Congo

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Overview of mpox in the Democratic Republic of the Congo


Mpox in the Democratic Republic of the Congo

Electron micrograph of the mpox virus.

Mpox, formerly known as monkeypox, is a viral zoonotic disease that occurs primarily in tropical rainforest areas of Central and West Africa. The Democratic Republic of the Congo (DRC) has been one of the most affected countries by this disease. The virus is part of the Orthopoxvirus genus, which also includes the variola virus, the causative agent of smallpox.

History

The first human case of mpox was recorded in the DRC in 1970. Since then, the country has experienced numerous outbreaks. The disease was initially identified in laboratory monkeys, which is how it got its name, but it is more commonly found in rodents and other small mammals.

Epidemiology

CDC illustration of the mpox virus.

The DRC has reported thousands of cases of mpox over the years, with the disease being endemic in the region. The virus is transmitted to humans through close contact with an infected animal or person, or with material contaminated with the virus. Human-to-human transmission is limited but can occur through respiratory droplets, contact with bodily fluids, or lesions of an infected person.

Symptoms

The symptoms of mpox in humans are similar to those of smallpox, but generally milder. They include fever, headache, muscle aches, and a characteristic rash that often begins on the face before spreading to other parts of the body. The rash progresses through several stages before forming a scab and eventually falling off.

Diagnosis and Treatment

Diagnosis of mpox is based on clinical presentation and can be confirmed by laboratory testing, including polymerase chain reaction (PCR) and virus isolation. There is no specific treatment for mpox, but supportive care and management of complications can improve outcomes. Vaccination against smallpox has been shown to provide some protection against mpox.

Prevention

Mpox lesions on a patient's arm.

Preventive measures include avoiding contact with animals that could harbor the virus, practicing good hygiene, and using personal protective equipment when caring for infected individuals. Public health education and surveillance are crucial in controlling outbreaks.

Challenges

The DRC faces significant challenges in controlling mpox due to limited healthcare infrastructure, ongoing conflict, and other public health priorities such as Ebola virus disease and malaria.

Related pages

Close-up of mpox lesions.
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Contributors: Prab R. Tumpati, MD