Morphine-N-oxide

Morphine-N-oxide is a drug that belongs to the class of opioids. It is a minor metabolite of morphine, which is a naturally occurring substance extracted from the seed pod of certain varieties of poppy plants.

Chemistry

Morphine-N-oxide is a chemical compound with the molecular formula C17H19NO4. It is an organic compound that contains a morphine core structure, with an oxide group attached to the nitrogen atom. This modification results in a compound with different pharmacological properties compared to morphine.

Pharmacology

Morphine-N-oxide acts on the central nervous system (CNS) to produce its effects. It binds to opioid receptors in the brain and spinal cord, which are involved in the transmission and perception of pain. By binding to these receptors, Morphine-N-oxide can block the transmission of pain signals, providing analgesic effects.

Clinical Use

Morphine-N-oxide is not typically used in clinical practice due to its lower potency compared to morphine. However, it may be produced in the body as a metabolite when morphine is administered. The clinical significance of this metabolite is not fully understood, and further research is needed to determine its potential therapeutic or adverse effects.

Side Effects

As with other opioids, Morphine-N-oxide can cause a range of side effects. These may include drowsiness, nausea, constipation, and respiratory depression. It can also cause dependence and withdrawal symptoms if used for prolonged periods.

See Also

• Morphine
• Opioid
• Opioid receptor
• Central nervous system

References

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Morphine-N-oxide

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  Morphine N-oxide structure