Monomelic amyotrophy
Monomelic Amyotrophy (pronunciation: mo-no-me-lic a-my-o-tro-phy) is a rare type of neuromuscular disease that primarily affects the nervous system. The term is derived from the Greek words mono meaning single, melos meaning limb, and atrophy referring to the wasting away or decrease in size of an organ or tissue in the body.
Definition
Monomelic Amyotrophy (MMA) is a condition characterized by progressive degeneration and loss of motor neurons, the nerve cells in the brain and spinal cord that are responsible for controlling voluntary muscles. This condition predominantly affects only one limb, usually the arm and hand rather than the leg.
Symptoms
The symptoms of Monomelic Amyotrophy typically begin in adolescence or early adulthood and progress slowly over a period of years. The most common symptoms include weakness, muscle wasting, and fasciculations (muscle twitching) in a single limb.
Causes
The exact cause of Monomelic Amyotrophy is unknown. However, it is believed to be related to the degeneration of motor neurons in the spinal cord. Some researchers suggest that it may be an autoimmune disorder, while others believe it may be due to a viral infection.
Diagnosis
Diagnosis of Monomelic Amyotrophy is based on the clinical symptoms, neurological examination, and electromyography (EMG) which measures the electrical activity of muscles.
Treatment
There is currently no cure for Monomelic Amyotrophy. Treatment is focused on managing symptoms and improving the quality of life. This may include physical therapy, occupational therapy, and the use of assistive devices.
Prognosis
The prognosis for individuals with Monomelic Amyotrophy varies. Some individuals may experience a slow progression of symptoms over many years, while others may experience a more rapid progression.
See Also
External links
- Medical encyclopedia article on Monomelic amyotrophy
- Wikipedia's article - Monomelic amyotrophy
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