Modic changes
Modic Changes
Modic changes (/ˈmoʊdɪk/ changes) are pathological changes in the bones of the spine, specifically in the vertebral body marrow and endplates. These changes are named after Dr. Michael Modic, who first described them in 1988.
Etymology
The term "Modic changes" is derived from the name of Dr. Michael Modic, an American radiologist who first identified and described these changes in the late 20th century.
Types of Modic Changes
There are three types of Modic changes, each representing different stages of degeneration:
- Modic Type 1 changes: These changes represent acute inflammation and are characterized by hypointense T1 and hyperintense T2 signal changes.
- Modic Type 2 changes: These changes represent fatty degeneration and are characterized by hyperintense T1 and T2 signal changes.
- Modic Type 3 changes: These changes represent subchondral sclerosis and are characterized by hypointense T1 and T2 signal changes.
Clinical Significance
Modic changes are associated with low back pain and disc degeneration. They are often found in patients with degenerative disc disease and can be seen on magnetic resonance imaging (MRI) scans. The presence of Modic changes can influence the treatment plan for patients with back pain.
Related Terms
- Vertebral endplate: The end of a vertebra that faces an intervertebral disc.
- Marrow changes: Changes in the bone marrow, often associated with disease or injury.
- Degenerative disc disease: A condition characterized by the breakdown of the intervertebral discs, often resulting in pain and disability.
See Also
External links
- Medical encyclopedia article on Modic changes
- Wikipedia's article - Modic changes
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