Metronomic therapy

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Metronomic therapy is a type of chemotherapy that involves the administration of low doses of chemotherapeutic drugs over a prolonged period of time, with minimal breaks. This approach is designed to minimize toxicity and target the endothelial cells lining the blood vessels that feed tumors, rather than the tumor cells themselves.

Pronunciation

Metronomic therapy is pronounced as meh-truh-NAH-mik ther-uh-pee.

Etymology

The term "metronomic" is derived from the word "metronome," a device used by musicians to keep a steady tempo. This reflects the regular, rhythmic administration of chemotherapy drugs in this treatment approach. The term "therapy" comes from the Greek "therapeia," meaning "healing."

Related Terms

  • Chemotherapy: A type of cancer treatment that uses drugs to kill cancer cells.
  • Endothelial cells: Cells that line the interior surface of blood vessels and lymphatic vessels.
  • Tumor: An abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function.
  • Angiogenesis: The physiological process through which new blood vessels form from pre-existing vessels.

See Also

References

  • Kerbel, R. S., & Kamen, B. A. (2004). The anti-angiogenic basis of metronomic chemotherapy. Nature Reviews Cancer, 4(6), 423-436.
  • Pasquier, E., Kavallaris, M., & André, N. (2010). Metronomic chemotherapy: new rationale for new directions. Nature Reviews Clinical Oncology, 7(8), 455-465.

External links

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