Measles virus
(Redirected from Measles morbillivirus)
Measles virus is a single-stranded, negative-sense, enveloped RNA virus of the genus Morbillivirus within the family Paramyxoviridae. It is the cause of measles, a highly contagious disease in humans.
Structure
The measles virus is approximately 150 to 300 nanometers in diameter. It has a single-stranded RNA genome, which is surrounded by a lipid envelope. The envelope is studded with two types of glycoprotein spikes: hemagglutinin (H) and fusion (F) proteins.
Genome
The genome of the measles virus is approximately 16 kilobases in length. It encodes eight proteins: nucleocapsid protein (N), phosphoprotein (P), matrix protein (M), fusion protein (F), hemagglutinin (H), large protein (L), and two nonstructural proteins, C and V.
Replication
The measles virus enters the host cell by binding to the CD150 (SLAM) receptor on the cell surface. The virus then uncoats and releases its RNA genome into the cell. The viral RNA is transcribed into mRNA by the viral RNA-dependent RNA polymerase. The mRNA is then translated into viral proteins by the host cell's machinery. The newly synthesized viral proteins and RNA are assembled into new virus particles, which bud from the cell surface and are released to infect other cells.
Pathogenesis
The measles virus initially infects the respiratory tract. It then spreads to the lymphatic system and subsequently to other organs. The virus causes a characteristic rash, fever, and other symptoms of measles. Complications can include pneumonia, encephalitis, and subacute sclerosing panencephalitis (SSPE).
Prevention and control
Vaccination with the measles vaccine is the most effective way to prevent infection. The vaccine is usually given as part of the MMR (measles, mumps, rubella) or MMRV (measles, mumps, rubella, varicella) vaccine.
See also
Transform your life with W8MD's budget GLP-1 injections from $125.
W8MD offers a medical weight loss program to lose weight in Philadelphia. Our physician-supervised medical weight loss provides:
- Most insurances accepted or discounted self-pay rates. We will obtain insurance prior authorizations if needed.
- Generic GLP1 weight loss injections from $125 for the starting dose.
- Also offer prescription weight loss medications including Phentermine, Qsymia, Diethylpropion, Contrave etc.
NYC weight loss doctor appointments
Start your NYC weight loss journey today at our NYC medical weight loss and Philadelphia medical weight loss clinics.
- Call 718-946-5500 to lose weight in NYC or for medical weight loss in Philadelphia 215-676-2334.
- Tags:NYC medical weight loss, Philadelphia lose weight Zepbound NYC, Budget GLP1 weight loss injections, Wegovy Philadelphia, Wegovy NYC, Philadelphia medical weight loss, Brookly weight loss and Wegovy NYC
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
