Mannan
Mannan
Mannan is a type of polysaccharide that is composed of mannose monomers. It is a significant component of the cell walls of certain plants, fungi, and bacteria. Mannans are important in various biological processes and have applications in the food, pharmaceutical, and biotechnology industries.
Structure
Mannans are polysaccharides that consist of a backbone of β-1,4-linked mannose residues. The structure of mannan can vary depending on the source. In some organisms, mannans may have side chains or branches that include other sugars such as glucose or galactose. The degree of polymerization and branching can affect the physical properties and biological functions of the mannan.
Sources
Mannans are found in a variety of natural sources:
- Plants: In plants, mannans are found in the cell walls and serve as storage polysaccharides. They are particularly abundant in the seeds of legumes and in the endosperm of some plants, such as the ivory nut.
- Fungi: In fungi, mannans are a major component of the cell wall, where they are often linked to proteins to form mannoproteins.
- Bacteria: Some bacteria produce mannans as part of their extracellular polysaccharides.
Biological Functions
Mannans play several roles in biological systems:
- Structural Role: In plant cell walls, mannans contribute to the structural integrity and rigidity of the cell wall.
- Storage Role: In seeds, mannans serve as a reserve of energy and carbon that can be mobilized during germination.
- Immune Modulation: Mannans can interact with the immune system. For example, yeast mannans are known to activate the immune system and are studied for their potential as immunomodulatory agents.
Applications
Mannans have various applications in different industries:
- Food Industry: Mannans are used as thickeners, stabilizers, and emulsifiers in food products. Guar gum and locust bean gum are examples of mannan-based food additives.
- Pharmaceuticals: Mannans are explored for their potential in drug delivery systems and as adjuvants in vaccines.
- Biotechnology: Mannans are used in the production of biofuels and as substrates for the production of enzymes and other bioproducts.
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Contributors: Prab R. Tumpati, MD