MNS antigen system

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MNS Antigen System

The MNS antigen system (pronounced: em-en-es an-ti-gen sys-tem) is a human blood group system based upon two genes (glycophorin A and glycophorin B) on chromosome 4.

Etymology

The MNS antigen system is named after the first two antigens discovered in this system, M and N. The 'S' was added later when another antigen was discovered.

Description

The MNS antigen system is one of the 36 human blood group systems recognized by the International Society of Blood Transfusion (ISBT). The system consists of more than 40 antigens, the most important of which are M, N, S, s, and U. These antigens are found on the surface of red blood cells and are important in transfusion medicine.

Related Terms

  • Glycophorin A: A protein that carries the M and N antigens.
  • Glycophorin B: A protein that carries the S, s, and U antigens.
  • Antigen: A substance that can induce an immune response.
  • Blood group system: A classification of blood based on the presence or absence of inherited antigenic substances on the surface of red blood cells.
  • Transfusion medicine: The branch of medicine that is concerned with the transfusion of blood and blood components.

See Also

External links

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