MELISA

MELISA (Memory Lymphocyte Immunostimulation Assay) is a blood test used to identify hypersensitivity to various substances. It was developed by Vera Stejskal in the 1980s. The test is controversial and its use is generally not recommended by health authorities.

Overview

MELISA is a type of lymphocyte transformation test (LTT). It is used to detect hypersensitivity to various substances, including metals, chemicals, and biologicals. The test is based on the principle that lymphocytes (a type of white blood cell) from individuals who are hypersensitive to a particular substance will proliferate when exposed to that substance in vitro.

Procedure

In the MELISA test, a sample of the patient's blood is taken and the lymphocytes are isolated. These cells are then exposed to various substances in the laboratory. If the patient is hypersensitive to a particular substance, their lymphocytes will proliferate in response to exposure to that substance. The degree of proliferation is measured and used to determine the level of hypersensitivity.

Controversy

The use of MELISA is controversial. Many health authorities, including the American Dental Association and the Food and Drug Administration, do not recommend its use. Critics argue that the test has not been adequately validated and that it can produce false positive results. Proponents of the test argue that it can help identify the cause of various health problems, including chronic fatigue syndrome, fibromyalgia, and multiple chemical sensitivity.

See also

• Allergy
• Immunology
• Lymphocyte
• Hypersensitivity

References

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