Luteolysis
Luteolysis (pronounced: loo-tee-oh-LY-sis) is a physiological process that occurs in the female reproductive system. It involves the degeneration of the corpus luteum, a temporary endocrine structure in female mammals, which is involved in the production of relatively high levels of progesterone, a hormone necessary for the maintenance of pregnancy.
Etymology
The term "luteolysis" is derived from the Latin luteus, meaning "yellow", and the Greek lysis, meaning "loosening" or "dissolution". This refers to the breakdown of the yellowish corpus luteum.
Process
Luteolysis begins after the ovulation phase of the menstrual cycle if fertilization of the egg does not occur. The corpus luteum, which is responsible for the production of progesterone, begins to degenerate. This leads to a decrease in progesterone levels, which in turn triggers the onset of menstruation.
Regulation
The process of luteolysis is regulated by several hormones, including prostaglandin F2alpha (PGF2α), which is produced by the uterus in most mammals. PGF2α is responsible for initiating the process of luteolysis by inhibiting the secretion of progesterone.
Related Terms
See Also
External links
- Medical encyclopedia article on Luteolysis
- Wikipedia's article - Luteolysis
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