Legionella longbeachae
Legionella longbeachae is a gram-negative, flagellated, aerobic bacterium from the genus Legionella. It is one of the causative agents of Legionnaires' disease, a severe form of pneumonia. The bacterium was first isolated in 1980 from a patient in Long Beach, California, hence its name.
Characteristics
Legionella longbeachae is a rod-shaped bacterium that is motile due to its flagella. It is a facultative anaerobe, meaning it can grow in both oxygen-rich and oxygen-poor environments. The bacterium is also catalase and oxidase positive.
Pathogenesis
Legionella longbeachae is primarily found in soil and composted plant material, unlike other Legionella species which are typically associated with aquatic environments. Humans can become infected by inhaling dust contaminated with the bacteria. Once in the lungs, the bacteria invade and replicate within alveolar macrophages, leading to pneumonia.
Clinical Manifestations
The clinical manifestations of Legionella longbeachae infection are similar to those of other forms of Legionnaires' disease. Symptoms include fever, chills, cough, and shortness of breath. In severe cases, the infection can lead to respiratory failure and death.
Diagnosis and Treatment
Diagnosis of Legionella longbeachae infection is typically made by culture of respiratory secretions, urine antigen testing, or PCR. Treatment usually involves antibiotics such as macrolides or quinolones.
Prevention
Prevention of Legionella longbeachae infection involves avoiding exposure to dust from soil and compost, particularly for individuals with weakened immune systems or chronic lung disease.
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Contributors: Prab R. Tumpati, MD