Latanoprost/timolol

Latanoprost/timolol is a medication that combines two active ingredients, Latanoprost and Timolol, used primarily in the treatment of glaucoma and ocular hypertension. It is marketed under various brand names, including Xalacom.

Composition

The medication is a combination of two active ingredients:

• Latanoprost: A prostaglandin analogue that works by increasing the outflow of aqueous fluid from the eyes.
• Timolol: A non-selective beta blocker that works by reducing the production of aqueous fluid in the eyes.

Uses

Latanoprost/timolol is used to reduce intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to topical beta-blockers or prostaglandin analogues.

Side Effects

Possible side effects of Latanoprost/timolol include:

• Changes in eye color
• Blurred vision
• Eye discomfort
• Stinging or burning in the eye
• Increased sensitivity to light

Contraindications

Latanoprost/timolol is contraindicated in patients with:

• Reactive airway disease including bronchial asthma or a history of bronchial asthma, severe chronic obstructive pulmonary disease
• Sinus bradycardia, second or third degree atrioventricular block, overt cardiac failure, cardiogenic shock
• Hypersensitivity to either component of this product or to any of the excipients

Interactions

Latanoprost/timolol can interact with other medications, including:

• Other eye drops or eye medications
• Beta-blockers or calcium channel blockers for high blood pressure
• Medications for heart disease or diabetes

See Also

• Glaucoma
• Ocular hypertension
• Latanoprost
• Timolol

References

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