Lambert-Eaton syndrome

Lambert-Eaton Syndrome

Lambert-Eaton Syndrome (pronounced lam-bert ee-ton sin-drome), also known as Lambert-Eaton Myasthenic Syndrome (LEMS), is a rare autoimmune disease that affects the neuromuscular junction.

Etymology

The syndrome is named after two physicians, Edward Lambert and Lee Eaton, who first described the condition in 1956.

Definition

Lambert-Eaton Syndrome is a disorder in which the immune system attacks the neuromuscular junctions - the areas where your nerves and muscles connect. This leads to muscle weakness and other symptoms.

Symptoms

The main symptoms of Lambert-Eaton Syndrome include:

Muscle weakness
Fatigue
Difficulty swallowing (Dysphagia)
Difficulty speaking (Dysarthria)
Dry mouth
Impaired sweating

Causes

Lambert-Eaton Syndrome is often associated with a type of cancer called Small cell lung cancer. However, it can also occur in people without cancer. The exact cause of the syndrome is unknown, but it is thought to be related to an abnormal immune response.

Diagnosis

Diagnosis of Lambert-Eaton Syndrome is typically made through a combination of clinical examination, medical history, and specialized tests such as Electromyography (EMG) and blood tests for specific antibodies.

Treatment

Treatment for Lambert-Eaton Syndrome typically involves managing the symptoms and, if applicable, treating the underlying cancer. Medications such as Pyridostigmine may be used to improve muscle strength. In severe cases, Immunotherapy or Plasmapheresis may be recommended.

Related Terms

External links

Medical encyclopedia article on Lambert-Eaton syndrome
Wikipedia's article - Lambert-Eaton syndrome

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Lambert-Eaton syndrome