LMNA

LMNA

The LMNA gene, pronounced as /ˈɛlˈɛmˈɛnˈeɪ/, is a gene that provides instructions for making a protein called lamin A and lamin C. These proteins are a part of the Nuclear Lamina, a matrix of proteins located on the inner edge of the Nuclear Envelope.

Etymology

The term "LMNA" is an abbreviation derived from the words "Lamin A/C". The name "lamin" comes from the Latin word "lamina", which means "thin layer".

Function

The proteins produced by the LMNA gene, lamin A and lamin C, play crucial roles in determining the shape and stability of the nucleus. They are involved in various nuclear activities, including DNA replication and cell division.

Related Terms

• Laminopathy: A disease caused by mutations in the LMNA gene.
• Hutchinson-Gilford Progeria Syndrome: A rare, progressive genetic disorder caused by a mutation in the LMNA gene.
• Mandibuloacral Dysplasia: A condition characterized by growth retardation and bone abnormalities, often caused by mutations in the LMNA gene.

See Also

• Gene
• Protein
• Nuclear Lamina
• Nuclear Envelope
• Nucleus (cell)

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