Keratosis follicularis

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Keratosis Follicularis

Keratosis Follicularis (pronunciation: kuh-rah-toh-sis fuh-li-kyuh-lair-is), also known as Darier's Disease, is a rare, genetic skin disorder.

Etymology

The term "Keratosis Follicularis" is derived from the Greek word 'keras' meaning 'horn', and 'osis' meaning 'condition'. 'Follicularis' is derived from the Latin word 'folliculus' meaning 'small bag'. The term thus refers to a condition where the hair follicles develop a horn-like appearance.

Definition

Keratosis Follicularis is characterized by the presence of small, hard bumps on the skin, particularly in areas where there is a high concentration of hair follicles. These bumps are often rough to the touch and may be accompanied by itching or discomfort.

Symptoms

The primary symptom of Keratosis Follicularis is the presence of small, hard bumps on the skin. These bumps are often rough to the touch and may be accompanied by itching or discomfort. Other symptoms may include redness, inflammation, and in severe cases, infection.

Causes

Keratosis Follicularis is a genetic disorder, meaning it is passed down through families. It is caused by a mutation in the ATP2A2 gene, which is responsible for regulating the levels of calcium in the skin cells.

Treatment

Treatment for Keratosis Follicularis primarily involves managing the symptoms. This may include the use of topical creams to reduce inflammation and itching, as well as oral medications to manage any infections. In severe cases, surgical intervention may be necessary.

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