KRT1
KRT1 (pronounced as "kay-are-tee-one"), also known as Keratin 1, is a protein that in humans is encoded by the KRT1 gene.
Etymology
The term "KRT1" is an abbreviation for "Keratin 1". The word "Keratin" is derived from the Greek word "κέρας" (keras), meaning "horn". This is a reference to the protein's toughness and its role in the formation of structures that require resilience and rigidity, such as hair, nails, and the outer layer of skin.
Function
KRT1 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs with type II cytokeratins, a basic protein.
Related Terms
- Keratin: A type of protein that makes up your hair, skin, and nails. Keratins are also found in your internal organs and glands.
- Gene: The basic physical and functional unit of heredity. Genes are made up of DNA.
- Protein: A molecule composed of polymers of amino acids joined together by peptide bonds.
- Epithelial Cells: Cells that line the surfaces of your organs and body cavities, making up a large portion of your body tissues.
- Cytokeratins: A type of intermediate filament protein, which are insoluble and tough and form strong unmineralized tissues found in reptiles, birds, amphibians, and mammals.
See Also
References
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