JT-010

JT-010

Chemical structure of JT-010

JT-010 is a chemical compound known for its role as a selective agonist of the TRPV1 receptor, which is a member of the transient receptor potential channel family. These channels are involved in various physiological processes, including the sensation of pain, temperature, and inflammation.

Chemical Properties

JT-010 is characterized by its unique chemical structure, which allows it to interact specifically with the TRPV1 receptor. The compound's molecular formula is C₂₀H₁₉ClN₂O₂, and it has a molecular weight of 354.83 g/mol.

Mechanism of Action

JT-010 functions by binding to the TRPV1 receptor, which is a non-selective cation channel. This receptor is activated by various stimuli, including capsaicin, heat, and protons. Upon activation by JT-010, the TRPV1 receptor undergoes a conformational change that allows the influx of calcium and sodium ions, leading to neuronal depolarization and the transmission of pain signals.

Pharmacological Effects

The activation of TRPV1 by JT-010 has been studied for its potential therapeutic effects in managing chronic pain and inflammatory conditions. By modulating the activity of TRPV1, JT-010 may help in reducing pain perception and inflammation.

Research and Development

Research on JT-010 is ongoing, with studies focusing on its efficacy and safety profile in various animal models. The compound's selectivity for TRPV1 makes it a valuable tool in understanding the physiological and pathological roles of this receptor.

Related Pages

• TRPV1
• Transient receptor potential channel
• Capsaicin
• Chronic pain