Intrinsic immunity

Intrinsic immunity refers to the body's innate, non-specific defense mechanisms that come into play immediately or within hours of an antigen's appearance in the body. These mechanisms include physical barriers such as skin, chemicals in the blood, and immune system cells that attack foreign cells in the body.

Overview

The immune system is divided into two categories: innate and adaptive. Intrinsic immunity is a part of the innate immune system, which is present at birth. It provides the first line of defense against pathogens and is non-specific, meaning it does not respond differently to different pathogens.

Mechanisms of Intrinsic Immunity

Intrinsic immunity involves various mechanisms to protect the body from pathogens. These include:

• Physical barriers: The skin and mucous membranes act as physical barriers preventing pathogens from entering the body.
• Chemical barriers: Certain chemicals in the body, such as stomach acid and enzymes in tears and skin oils, destroy pathogens.
• Cellular defenses: Certain cells in the immune system, such as natural killer cells, macrophages, and neutrophils, attack and destroy pathogens.

Role in Disease Prevention

Intrinsic immunity plays a crucial role in preventing diseases by providing immediate defense against pathogens. It also helps in activating the adaptive immune system, which provides a more specific and long-lasting defense against pathogens.

See Also

• Innate immunity
• Adaptive immunity
• Immune system
• Pathogen

References

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