Intraneural perineurioma

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An intraneural perineurioma is a rare benign tumor within the sheath of a single nerve that grows but typically does not recur or metastasize. These lesions are only composed of perineurial cells, cloned from a single cell. They are distinct from schwannoma and neurofibroma.

"Intraneural perineurioma is a neoplastic proliferation of perineurial cells with unique immunohistochemistry and ultrastructural features, and it is distinct from other onion bulb Schwann cell-derived entities. Despite harboring molecular abnormalities of the long arm of chromosome 22, intraneural perineurioma has not been associated with neurofibromatosis."[1]

References[edit]

  1. "Intraneural perineurioma: a systematic review with illustrative cases".Archives of Pathology & Laboratory Medicine.2007;131(9)
    1382–92.doi:[1382:IPASRW2.0.CO;2 10.1043/1543-2165(2007)131[1382:IPASRW]2.0.CO;2].PMID:17824794.

Further reading[edit]

  • "Perineurioma: a distinctive and underrecognized peripheral nerve sheath neoplasm".Archives of Pathology & Laboratory Medicine.2007;131(4)
625–36.doi:[625:PADAUP2.0.CO;2 10.1043/1543-2165(2007)131[625:PADAUP]2.0.CO;2].PMID:17425397.
  • "Intraneural reticular perineurioma of the hypoglossal nerve.".Head Neck..2009;31(6)
833–7.doi:10.1002/hed.20965.PMID:18972430.
  • "Surgical removal of intraneural perineurioma arising in the brachial plexus using an interfascicular dissection technique".Arch Plast Surg.2014;41(3)
296–9.doi:10.5999/aps.2014.41.3.296.PMID:24883285.PMC:4037780.
  • "Intraneural perineurioma. A clonal neoplasm associated with abnormalities of chromosome 22".Am J Clin Pathol.1995;103(6)
696–704.doi:10.1093/ajcp/103.6.696.PMID:7785653.

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