Influenza C virus

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Influenza C Virus

Electron micrograph of the influenza virus

The Influenza C virus is a member of the Orthomyxoviridae family, which also includes Influenza A virus and Influenza B virus. Unlike its counterparts, Influenza C is less common and typically causes mild respiratory illnesses in humans. It is known to infect both humans and pigs, and it is less likely to cause epidemics.

Structure

Influenza C virus is an enveloped virus with a segmented, single-stranded, negative-sense RNA genome. The virus has seven segments, which encode nine proteins. The surface of the virus is covered with a glycoprotein called hemagglutinin-esterase-fusion (HEF) protein, which combines the functions of hemagglutinin and neuraminidase found in Influenza A and B viruses.

Transmission

The virus is transmitted through respiratory droplets from coughing and sneezing. It can also spread through contact with contaminated surfaces. Influenza C infections are more common in children and can occur throughout the year, although they are more frequent in the winter months.

Symptoms

Infections with Influenza C virus typically result in mild respiratory symptoms, such as:

In some cases, it can lead to more severe respiratory illnesses, especially in young children and individuals with weakened immune systems.

Diagnosis

Diagnosis of Influenza C virus infection is usually made through polymerase chain reaction (PCR) testing of respiratory specimens. Serological tests can also be used to detect antibodies against the virus.

Treatment

There is no specific antiviral treatment for Influenza C virus infections. Management typically involves supportive care, such as rest, fluids, and over-the-counter medications to relieve symptoms. In severe cases, hospitalization may be required.

Prevention

Preventive measures include practicing good hygiene, such as frequent handwashing and covering the mouth and nose when coughing or sneezing. There is currently no vaccine available for Influenza C virus.

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Contributors: Prab R. Tumpati, MD