Inflammatory pseudotumor

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Inflammatory Pseudotumor

Inflammatory pseudotumor (pronounced: in-flam-ma-tor-ee soo-doh-too-mor) is a term used to describe a non-neoplastic, non-infectious mass-like lesion that is characterized by a proliferative fibro-inflammatory reaction. The etymology of the term is derived from the Greek words "pseudo", meaning false, and "tumor", meaning swelling.

Definition

An inflammatory pseudotumor is a benign condition that mimics a malignant tumor both clinically and radiologically. It is characterized by an unexplained growth of cells, which can occur in various parts of the body, including the lung, liver, eye, and central nervous system. Despite its name, it is not a true tumor, but rather an inflammatory response that results in a mass-like lesion.

Symptoms

Symptoms of an inflammatory pseudotumor can vary depending on the location of the lesion. Common symptoms may include pain, swelling, and functional impairment of the affected organ. In some cases, systemic symptoms such as fever, weight loss, and malaise may also be present.

Diagnosis

Diagnosis of an inflammatory pseudotumor typically involves imaging studies such as CT scans or MRI, and often requires a biopsy for definitive diagnosis. The histological features of an inflammatory pseudotumor include a mixture of inflammatory cells and myofibroblastic proliferation.

Treatment

Treatment options for an inflammatory pseudotumor depend on the location and size of the lesion, as well as the patient's overall health. Treatment may include surgical resection, corticosteroid therapy, or radiotherapy. In some cases, no treatment is necessary and the lesion may resolve on its own.

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