Indolent
Indolent is a term often used in medicine to describe a disease condition that progresses slowly and with less severe symptoms. It is commonly used in the context of certain types of cancer, such as indolent lymphomas, which grow slowly and typically cause fewer symptoms than aggressive lymphomas.
Definition
The term "indolent" is derived from the Latin word "indolens", meaning "not suffering". In a medical context, it is used to describe a disease that is slow-growing or slow to change. This is in contrast to more aggressive diseases, which progress rapidly and cause severe symptoms.
Indolent Diseases
Indolent diseases are often chronic and progress slowly over time. They may cause fewer symptoms than more aggressive diseases, and patients with indolent diseases may have a better prognosis. Examples of indolent diseases include certain types of cancer, such as indolent lymphomas and indolent prostate cancer.
Indolent Lymphomas
Indolent lymphomas are a type of Non-Hodgkin lymphoma that grow slowly. They include follicular lymphoma, small lymphocytic lymphoma, and marginal zone lymphoma. These types of lymphoma may not require immediate treatment and can often be managed with a "watch and wait" approach.
Indolent Prostate Cancer
Indolent prostate cancer is a type of prostate cancer that grows slowly and may not cause symptoms or require immediate treatment. It is often detected through routine screening tests and may be managed with active surveillance.
Treatment
The treatment of indolent diseases depends on the specific disease and the patient's overall health. In some cases, a "watch and wait" approach may be appropriate. In other cases, treatment may include surgery, radiation therapy, chemotherapy, or targeted therapies.
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Contributors: Prab R. Tumpati, MD