Icatibant
Icatibant (pronounced as i-kat-i-bant) is a synthetic peptide and a selective antagonist of the bradykinin B2 receptor. It is primarily used in the treatment of Hereditary Angioedema (HAE).
Etymology
The term "Icatibant" is derived from its chemical structure. The 'I' stands for iso, 'cati' for cationic, and 'bant' for bradykinin antagonist.
Pharmacology
Icatibant works by blocking the bradykinin receptor, which is involved in the dilation of blood vessels and pain sensation. By blocking this receptor, Icatibant helps to reduce the symptoms of HAE, such as swelling and pain.
Usage
Icatibant is used to treat acute attacks of hereditary angioedema (HAE) in adults. It is administered as a subcutaneous injection.
Side Effects
Common side effects of Icatibant include injection site reactions, fever, increased liver enzymes, dizziness, and rash. Severe side effects may include difficulty breathing or swallowing.
Related Terms
See Also
External links
- Medical encyclopedia article on Icatibant
- Wikipedia's article - Icatibant
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