IRF2
IRF2
Interferon regulatory factor 2 (IRF2) is a protein that in humans is encoded by the IRF2 gene. It is a member of the interferon regulatory transcription factor (IRF) family. IRF2 competes with IRF1 for binding to the interferon-stimulated response element (ISRE) in interferon-mediated gene expression.
Function[edit]
IRF2 is a transcriptional repressor that binds to the ISRE and represses interferon-stimulated transcription. In addition, IRF2 has been shown to repress transcription via other mechanisms, and it is thought to play a role in the cellular response to viral infection.
Clinical significance[edit]
Mutations in the IRF2 gene have been associated with a variety of diseases, including autoimmune diseases, cancer, and viral infections. The role of IRF2 in these diseases is not fully understood, but it is thought to be involved in the regulation of the immune response.
See also[edit]
References[edit]
External links[edit]
 | This medical article is a stub. You can help WikiMD by expanding the page. |
Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
