Hoover's sign (pulmonary)

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Hoover's Sign (Pulmonary) is a clinical sign indicative of chronic obstructive pulmonary disease (COPD). It is named after Charles Franklin Hoover, who first described it. This sign is observed during the physical examination of a patient and is used to assess the function of the diaphragm, the primary muscle involved in breathing.

Clinical Presentation

Hoover's sign is characterized by the inward movement of the lower rib cage during inspiration, instead of the normal outward expansion. This paradoxical movement is due to the increased effort required to breathe when the lungs are hyperinflated, as seen in advanced stages of COPD. Hyperinflation leads to flattening of the diaphragm, reducing its mechanical advantage and resulting in the use of accessory muscles for respiration.

Pathophysiology

In patients with COPD, airflow limitation is primarily caused by a combination of airway and parenchymal damage. The airway damage leads to obstruction, while the parenchymal damage causes a decrease in elastic recoil, both contributing to air trapping and lung hyperinflation. The diaphragm, being a dome-shaped muscle, operates most efficiently when it is appropriately domed. However, in the hyperinflated lungs of COPD patients, the diaphragm is flattened and placed at a mechanical disadvantage, making inspiration more difficult and leading to the use of accessory muscles for breathing.

Diagnosis

Hoover's sign is detected during the physical examination. The examiner places their hands on the patient's lower rib cage and observes the movement during inspiration. The presence of Hoover's sign is indicative of diaphragmatic dysfunction and is often associated with severe COPD. However, it is not specific to COPD and may be observed in other conditions that lead to diaphragmatic weakness or paralysis.

Clinical Significance

The presence of Hoover's sign in a patient with respiratory symptoms suggests advanced lung disease and significant diaphragmatic dysfunction. It is a useful clinical marker for assessing the severity of COPD and may guide the clinician in the management and treatment of the condition. Patients with a positive Hoover's sign may require more aggressive treatment strategies and closer monitoring.

Management

Management of patients with Hoover's sign focuses on the underlying COPD. Treatment options include bronchodilators, corticosteroids, pulmonary rehabilitation, and oxygen therapy. Smoking cessation is crucial in all patients. In severe cases, surgical interventions such as lung volume reduction surgery or lung transplantation may be considered.

See Also


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Contributors: Prab R. Tumpati, MD