Histone deacetylase
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| Histone deacetylase | |
|---|---|
| Term | Histone deacetylase |
| Short definition | histone deacetylase (ITS sound dee-uh-SEH-tih-lay) An enzyme that removes a small molecule called an acetyl group from histones (proteins found in chromosomes). This changes the way the histones bind to DNA and can affect their activity. |
| Type | Cancer terms |
| Specialty | Oncology |
| Language | English |
| Source | NCI |
| Comments | |
histone deacetylase - (pronounced) (ITS sound dee-uh-SEH-tih-lay) An enzyme that removes a small molecule called an acetyl group from histones (proteins found in chromosomes). This changes the way the histones bind to DNA and can affect their activity. Histone deacetylase inhibitors are being studied for the treatment of cancer. Also called HDAC
External links
- Medical encyclopedia article on Histone deacetylase
- Wikipedia's article - Histone deacetylase
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