Heterologous vaccine

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Heterologous Vaccine

Heterologous vaccine (pronunciation: /ˌhɛtəˈrɑːləɡəs vaksin/) is a type of vaccine that is derived from a different species, or a different disease-causing organism, than the one against which the vaccine is intended to protect.

Etymology

The term "heterologous" is derived from the Greek words "heteros" meaning "other" and "logos" meaning "relation". In the context of vaccines, it refers to the use of a different, but related, organism or species to stimulate an immune response.

Usage

Heterologous vaccines are often used when the pathogen of interest is difficult to culture or manipulate genetically. They can also be used to stimulate a broader immune response than would be possible with a homologous vaccine. Examples of heterologous vaccines include the BCG vaccine for tuberculosis, which is derived from a strain of Mycobacterium bovis, and the vaccinia vaccine for smallpox, which is derived from the vaccinia virus.

Related Terms

  • Vaccine: A biological preparation that provides active acquired immunity to a particular infectious disease.
  • Homologous vaccine: A vaccine that is derived from the same species or the same disease-causing organism against which the vaccine is intended to protect.
  • BCG vaccine: A vaccine primarily used against tuberculosis.
  • Mycobacterium bovis: A species of bacteria that can cause tuberculosis in cattle and other animals.
  • Vaccinia virus: A virus that is used as a vaccine to protect against smallpox.

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