HLA-DQ1
HLA-DQ1
HLA-DQ1 is a serotype group within the HLA-DQ serotype system, part of the Human leukocyte antigen (HLA) system. The HLA-DQ1 serotype group includes the HLA-DQ1.1, HLA-DQ1.2, and HLA-DQ1.3 subtypes.
Pronunciation
HLA-DQ1 is pronounced as "H-L-A-D-Q-one".
Etymology
The term "HLA-DQ1" is derived from the Human leukocyte antigen system, which is a group of genes that play a crucial role in the regulation of the immune system in humans. The "DQ" in HLA-DQ1 refers to the DQ serotype within the HLA system, and the "1" denotes the specific serotype group.
Related Terms
- HLA-DQ: The serotype system that HLA-DQ1 is a part of.
- Human leukocyte antigen: The overall system of genes that HLA-DQ1 belongs to.
- Serotype: A method of classifying microorganisms or viruses based on their cell surface antigens.
- Immune system: The bodily system that fights off pathogens and diseases, which the HLA system is a crucial part of.
Function
HLA-DQ1 is involved in the immune response. It presents antigens to T-cells, which then trigger an immune response. This is a crucial part of the body's defense against pathogens.
Clinical Significance
HLA-DQ1 has been associated with a number of autoimmune diseases, including Celiac disease, Multiple sclerosis, and Type 1 diabetes. It is thought that certain variations in the HLA-DQ1 genes may increase susceptibility to these diseases.
External links
- Medical encyclopedia article on HLA-DQ1
- Wikipedia's article - HLA-DQ1
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