Goeckerman therapy

Goeckerman Therapy

William H. Goeckerman, MD

Goeckerman therapy is a treatment regimen for psoriasis that combines the application of crude coal tar with exposure to ultraviolet light. This therapy was developed in the 1920s by William H. Goeckerman, a dermatologist at the Mayo Clinic.

History

Goeckerman therapy was first introduced by Dr. William H. Goeckerman in 1925. At the time, psoriasis was a challenging condition to treat, and Dr. Goeckerman's method provided a significant improvement in patient outcomes. The therapy was based on the observation that coal tar had been used for centuries to treat skin conditions, and ultraviolet light was known to have beneficial effects on psoriasis.

Mechanism of Action

The effectiveness of Goeckerman therapy is attributed to the synergistic effects of coal tar and ultraviolet light. Coal tar is believed to have anti-inflammatory and antiproliferative properties, which help to slow down the rapid growth of skin cells seen in psoriasis. Ultraviolet light, particularly UVB, further aids in reducing inflammation and scaling.

Procedure

The Goeckerman regimen typically involves the daily application of crude coal tar to the affected areas of the skin, followed by exposure to UVB light. The treatment is usually conducted in a clinical setting, although home-based regimens have also been developed. The duration of the therapy can vary, but it often lasts for several weeks.

Efficacy

Goeckerman therapy has been shown to be highly effective in clearing psoriasis lesions. Many patients experience significant improvement or complete remission of their symptoms. However, the therapy requires a considerable time commitment and can be messy due to the nature of coal tar.

Side Effects

Common side effects of Goeckerman therapy include skin irritation, folliculitis, and a strong odor from the coal tar. Long-term use of coal tar has raised concerns about potential carcinogenicity, although studies have not conclusively demonstrated an increased risk of cancer with Goeckerman therapy.

Modern Use

While newer treatments for psoriasis, such as biologics, have become available, Goeckerman therapy remains a valuable option, particularly for patients who do not respond to other treatments or prefer a non-systemic approach. It is often used in specialized dermatology centers.

Related Pages

• Psoriasis
• Ultraviolet therapy
• Coal tar