Gareth Sanger

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Gareth Sanger is a renowned British pharmacologist, known for his significant contributions to the field of pharmacology.

Pronunciation

Gareth Sanger is pronounced as /ˈɡærɛθ ˈseɪndʒər/.

Etymology

The name Gareth is of Welsh origin, meaning "gentle". Sanger is a surname of German origin, meaning "singer".

Career

Gareth Sanger has made significant contributions to the field of pharmacology, particularly in the area of gastroenterology. He is known for his research on 5-HT receptors, which are a group of G protein-coupled receptors and ligand-gated ion channels found in the central and peripheral nervous systems.

Contributions

One of his notable contributions is the discovery of the 5-HT4 receptor agonist, prucalopride, a drug used for the treatment of chronic constipation. He also contributed to the development of alosetron, a 5-HT3 receptor antagonist used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women.

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