Gadoleic acid

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Gadoleic acid

Gadoleic Acid

Gadoleic acid, also known as docos-13-enoic acid, is a monounsaturated omega-9 fatty acid with the chemical formula C20H38O2. It is classified as a long-chain fatty acid due to its 20 carbon atoms. Gadoleic acid is commonly found in various natural sources, including fish oil, seal oil, and certain plant oils such as canola oil.

Properties

Gadoleic acid is a colorless to pale yellow liquid at room temperature. It has a molecular weight of approximately 310.51 g/mol. The double bond in its structure is located at the 13th carbon atom from the methyl end of the fatty acid chain.

Biological Importance

In the human body, gadoleic acid plays a role in various physiological processes. It is a component of cell membranes and is involved in maintaining membrane fluidity and flexibility. Gadoleic acid is also a precursor for the synthesis of other important compounds, such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), which are essential omega-3 fatty acids.

Dietary Sources

Dietary sources of gadoleic acid include fatty fish such as salmon and mackerel, as well as certain marine mammals like seals. Plant oils like canola oil and macadamia oil also contain varying amounts of gadoleic acid.

Health Benefits

Research suggests that gadoleic acid, along with other omega-9 fatty acids, may have potential health benefits. These may include supporting cardiovascular health by helping to maintain healthy cholesterol levels and reducing inflammation in the body.

Potential Risks

While gadoleic acid is generally considered beneficial in moderate amounts, excessive intake of omega-9 fatty acids like gadoleic acid may lead to weight gain and other health issues. It is important to consume these fats as part of a balanced diet.

References

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Contributors: Prab R. Tumpati, MD