Frei test

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Frei Test

The Frei Test (pronounced: /fraɪ tɛst/) is a diagnostic procedure used to detect the presence of Lymphogranuloma venereum, a sexually transmitted infection caused by the invasive serovars L1, L2, L2a or L3 of Chlamydia trachomatis. The test is named after its developer, Wilhelm Siegmund Frei, a German dermatologist.

Etymology

The term "Frei Test" is derived from the name of its inventor, Wilhelm Siegmund Frei, who first introduced the test in 1913. The word "test" comes from the Old French test, meaning "small vessel", which is a metaphor for a method of examination.

Procedure

The Frei Test involves the intradermal injection of a Frei antigen, which is a suspension of killed Chlamydia trachomatis bacteria. If the patient is infected with Lymphogranuloma venereum, a positive reaction will occur, characterized by the formation of a nodule at the site of injection within 48 hours.

Related Terms

  • Lymphogranuloma venereum: A sexually transmitted infection caused by the invasive serovars L1, L2, L2a or L3 of Chlamydia trachomatis.
  • Chlamydia trachomatis: A bacterium that causes several types of infections, including sexually transmitted infections and trachoma, an infection of the eye.
  • Intradermal injection: A method of injection in which the substance is injected into the dermis, one of the layers of the skin.
  • Antigen: A substance that induces an immune response in the body, especially the production of antibodies.

See Also

External links

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