Formate
Formate is a chemical compound that is a derivative of formic acid. It is an important intermediate in chemical synthesis and occurs naturally, most notably in some ants. The word "formate" is derived from the Latin word for ant, formica, referring to its early isolation by the distillation of ant bodies. Esters, salts, and the anion derived from formic acid are referred to as formates.
Chemical Structure
Formate is an anion with a single negative charge. Its chemical formula is HCOO−. It consists of a hydrogen atom bonded to a carboxyl group. The carboxyl group consists of a carbon atom double-bonded to an oxygen atom and single-bonded to another oxygen atom. The second oxygen atom carries the negative charge.
Natural Occurrence
Formate is found in nature as a component of the venom of ant species belonging to the Formicinae subfamily. It is also produced as a byproduct in the fermentation process of some bacteria.
Industrial Uses
Formate is used in several industries, including the textile industry for dyeing and finishing textiles, and in the leather industry for tanning leather. It is also used as a de-icing agent for airport runways and as a buffer agent in the production of paper pulp.
Health Effects
Exposure to formate can cause skin and eye irritation, and ingestion can lead to symptoms such as nausea, vomiting, and abdominal pain. Chronic exposure can lead to more serious health effects, including damage to the kidneys and liver.
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Contributors: Prab R. Tumpati, MD