Formate
Formate
Formate (pronounced: /ˈfɔːrmeɪt/) is a derivative of formic acid and is an important compound in biochemistry.
Etymology
The term "Formate" is derived from the Latin word forma, meaning form, and the suffix -ate, used in chemistry to denote a salt or ester of an acid.
Biochemistry
In biochemistry, formate is involved in the Formate-Hydrogenlyase pathway, where it is cleaved to carbon dioxide and hydrogen. It is also a product of the Pyruvate formate-lyase reaction, which is part of the Glycolysis pathway.
Medical Relevance
Formate is toxic and can cause metabolic acidosis, a condition characterized by an excess of acid in the body fluids. This is often seen in Methanol poisoning, where methanol is metabolically converted to formate.
Related Terms
- Formic Acid: The acid from which formate is derived.
- Methanol: A toxic alcohol that is metabolized to formate in the body.
- Metabolic Acidosis: A medical condition that can be caused by an excess of formate in the body.
- Glycolysis: A metabolic pathway that produces formate as a byproduct.
- Formate-Hydrogenlyase pathway: A biochemical pathway involving the cleavage of formate.
- Pyruvate formate-lyase: An enzyme that produces formate.
External links
- Medical encyclopedia article on Formate
- Wikipedia's article - Formate
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