Folliculogenesis

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Folliculogenesis

Folliculogenesis (pronounced: fuh-li-kyuh-loh-jen-uh-sis) is the maturation process of the ovarian follicle, a densely packed shell of somatic cells that contains an immature oocyte. This process is a part of the menstrual cycle in many mammals, including humans.

Etymology

The term "Folliculogenesis" is derived from the Latin word "folliculus", meaning "small bag", and the Greek word "genesis", meaning "origin" or "source".

Process

Folliculogenesis begins in the ovarian cortex with the activation of the primordial follicles, which are composed of an oocyte surrounded by a single layer of squamous granulosa cells. The process ends with the release of a mature oocyte during ovulation, ready for fertilization.

Stages

Folliculogenesis can be divided into several stages:

  • Primordial follicle stage: The initial stage where the follicle is composed of an oocyte surrounded by a single layer of squamous granulosa cells.
  • Primary follicle stage: The follicle grows in size and the oocyte increases in diameter.
  • Secondary follicle stage: The granulosa cells proliferate and the theca cells form around the follicle.
  • Antral follicle stage: A fluid-filled cavity known as the antrum forms within the follicle.
  • Preovulatory follicle stage: The follicle is fully mature and ready for ovulation.

Related Terms

  • Oocyte: The female germ cell involved in reproduction.
  • Ovarian follicle: A fluid-filled sac that contains an immature egg, or oocyte.
  • Ovulation: The release of an egg from the ovary.
  • Fertilization: The fusion of an egg and sperm cell.

See Also

External links

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