Follicular dendritic cells

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Follicular Dendritic Cells

Follicular dendritic cells (FDCs) are a type of immune cell that play a crucial role in the immune response. They are found primarily in the lymphoid tissues, such as the lymph nodes and spleen, where they interact with B cells to stimulate the production of antibodies.

Pronunciation

Follicular dendritic cells: /fəˈlɪkjʊlər dɛnˈdraɪtɪk ˈsɛlz/

Etymology

The term "follicular dendritic cells" is derived from their location and shape. "Follicular" refers to their location in the lymphoid follicles, while "dendritic" describes their tree-like shape (from the Greek dendron, meaning tree).

Function

FDCs play a key role in the immune response by presenting antigens to B cells. This interaction stimulates the B cells to differentiate into plasma cells, which produce antibodies that can neutralize the antigen.

Related Terms

  • Antigen: A substance that triggers an immune response when introduced into the body.
  • B cell: A type of white blood cell that produces antibodies in response to antigens.
  • Lymphoid tissue: Tissue in the body that produces, stores, or carries white blood cells that fight infection and disease.
  • Plasma cell: A type of white blood cell that produces a specific antibody in response to an antigen.

See Also

External links

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