Fluoroethyl

Fluoroethyl is a functional group in chemistry. It is a derivative of ethyl, with one or more hydrogen atoms replaced by fluorine atoms. The simplest example is 2-fluoroethyl, with the formula CH2FCH2.

Chemistry

Fluoroethyl compounds are often used in medicinal chemistry and drug design. They are typically synthesized by nucleophilic substitution of a halogenated ethyl group with a fluoride ion. The resulting compounds can have a variety of biological activities, depending on the specific structure and the presence of other functional groups.

Applications

Fluoroethyl compounds have a wide range of applications. They are used in the synthesis of pharmaceuticals, agrochemicals, and materials. Some fluoroethyl compounds are used as radiotracers in positron emission tomography (PET) imaging. For example, 2-Fluoroethyl-D-glucopyranoside is used as a tracer in PET imaging of the brain.

Safety

Like all chemicals, fluoroethyl compounds should be handled with care. They can be harmful or fatal if swallowed, inhaled, or absorbed through the skin. Appropriate safety measures should be taken when handling these compounds, including the use of personal protective equipment and proper ventilation.

See also

• Fluorine
• Ethyl group
• Medicinal chemistry
• Drug design
• Positron emission tomography

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