Flosequinan
Flosequinan
Flosequinan (pronounced as floh-SEK-win-an) is a type of pharmacological agent that was primarily used as a vasodilator in the treatment of congestive heart failure.
Etymology
The term 'Flosequinan' is derived from the systematic IUPAC name of the drug, which is 6-fluoro-3,4-dihydro-5-[1-(quinolin-6-ylcarbonyl)piperidin-4-yl]-1(2H)-naphthalenone.
Usage
Flosequinan was used to treat congestive heart failure, a condition where the heart is unable to pump blood efficiently. It worked by relaxing and widening blood vessels, which allowed blood to flow more easily and reduced the workload on the heart.
Related Terms
- Pharmacology: The branch of medicine that deals with the uses, effects, and modes of action of drugs.
- Vasodilator: A drug or other agent that causes the dilation (widening) of blood vessels.
- Congestive heart failure: A chronic progressive condition that affects the pumping power of the heart muscles.
- IUPAC: The International Union of Pure and Applied Chemistry, an organization that sets the standards for naming chemical compounds.
Side Effects
Like all medications, Flosequinan had potential side effects. These included hypotension (low blood pressure), headache, and fluid retention.
Withdrawal from Market
Flosequinan was withdrawn from the market due to concerns about increased mortality rates among those taking the drug in a long-term capacity. The withdrawal was based on the results of a study known as the PROFILE study.
External links
- Medical encyclopedia article on Flosequinan
- Wikipedia's article - Flosequinan
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