Factor I

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Factor I

Factor I (pronounced as /ˈfæk.tər aɪ/), also known as C3b inactivator, is a protein that in humans is encoded by the CFI gene. It is a member of the serine protease family and part of the complement system, a part of the immune system that enhances the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism.

Etymology

The term "Factor I" is derived from the Latin word 'factor', meaning 'maker' or 'doer', and the Roman numeral 'I', signifying its identification as the first factor in the complement system.

Function

Factor I is a crucial regulator of the complement system, which is a part of the immune system. It is responsible for the inactivation of the C3b and C4b complement proteins, preventing the over-activation of the immune response and protecting host tissues from damage.

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