FAP

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FAP
TermFAP
Short definitionFAP - An inherited condition in which many polyps (usually hundreds to thousands) form on the inner walls of the colon and rectum. Polyps are abnormal growths that can become cancer if not removed. 
TypeCancer terms
SpecialtyOncology
LanguageEnglish
SourceNCI
Comments


FAP - An inherited condition in which many polyps (usually hundreds to thousands) form on the inner walls of the colon and rectum. Polyps are abnormal growths that can become cancer if not removed. People with FAP have a very high risk of developing colon cancer early on, and also have an increased risk of developing cancers of the stomach, small intestine, pancreas, bile duct, liver, adrenal gland, thyroid, and brain. They can also have dental and eye problems, and benign (noncancerous) tumors in the stomach, small intestine, bones, soft tissues, skin, and adrenal glands. FAP is caused by mutations (changes) in a gene called APC that are inherited in an autosomal dominant manner. It's a kind of hereditary cancer syndrome. Also referred to as classic familial adenomatous polyposis, classic familial polyposis, classic FAP, and familial adenomatous polyposis

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